Orphan drug exclusivity gives pharmaceutical companies seven years of market protection for rare-disease treatments, driving development where profits were once impossible. Here's how it works, why it matters, and what's changing.
Archive: 2025/12
Opioid-induced adrenal insufficiency is a rare but dangerous side effect of long-term opioid use that can cause life-threatening crashes during stress. Learn the signs, who’s at risk, and how to get tested.
Proton pump inhibitors can severely reduce the effectiveness of certain antifungals like itraconazole by raising stomach pH. Learn which drugs interact, why it matters, and how to fix it.
Many people feel their antihistamines stop working over time, but true tolerance is rare. Learn why symptoms may worsen, how to safely increase doses, and what alternatives actually work better than switching pills.
Heparin-induced thrombocytopenia (HIT) is a rare but dangerous side effect of heparin that causes low platelets and dangerous blood clots. Learn the signs, risks, and what to do if you're on heparin.
Methadone can prolong the QT interval, increasing the risk of dangerous heart rhythms - especially when combined with other medications. Learn how to spot the warning signs and reduce your risk.
Understand how deductibles, copays, and coinsurance work together in your health plan. Learn what you pay, when, and how to avoid surprise medical bills.
Malignant hyperthermia is a rare but deadly reaction to certain anesthesia drugs. Learn the warning signs, how dantrolene saves lives, who's at risk, and what hospitals must do to prevent deaths.
Floaters and flashes are common with age but can signal serious eye problems. Learn what causes them, when they’re harmless, and when you need urgent care to prevent vision loss.
Learn how to safely manage dental anesthesia while on blood thinners. Discover when to stop or continue anticoagulants, what procedures are safe, and how dentists control bleeding without interrupting your medication.
Immunosuppressants can affect fertility and pregnancy outcomes. Learn which drugs are safe, which to avoid, and how to plan ahead for a healthy pregnancy while managing autoimmune disease or transplant rejection.
Herbal supplements can dangerously interact with blood thinners like warfarin and apixaban, causing life-threatening bleeding or clots. Learn which herbs are most risky and what you must do to stay safe.